Jayati Mookerjee Basu, M.Tech., Ph.D.
Chittaranjan National Cancer Institute
Metabolic Regulation
37, S. P. Mukherjee Road
Kolkata - 700 026
West Bengal
E-mail: jayatimookerjee.basu@cnci.org.in
Phone: +91-33-24765101, Extn.330
Fax: +91-33-4757606
URL: http://www.cnci.org.in/research/research_main.html#
Positions Held:
Position Affiliation Time Period
Senior Scientific Officer, Gr-II
Chittaranjan National Cancer Institute, Kolkata, India
2010-Present
Post Doctoral Research Associate
University of Wisconsin-Madison, Madison, WI
2009-2009
Post Doctoral Fellow
INSERM, France
2007-2009
Post Doctoral Fellowship
Department of Biotechnology, Government of India
2006-2007
Area of Specialization:
Immunology
Research Summary:
To study the silencing of acquired and innate immune mechanisms in the tumor microenvironment
To develop gamma or delta T-cell and NKT cell based vaccinations for different cancers
Tumor cell metabolism and modulation of the tumor microenvironment towards development of new therapeutics
Publications:
1.
Lee, H. O., He, X., Mookerjee-Basu , J., Zhongping, D., Hua, X., Nicolas, E., Sulis, M. L., Ferrando, A. A., Testa, J. R. and Kappes, D. J. Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 2015. 112, 7773-7778. [PubMed]
2.
Mookerjee-Basu, J. and Kappes, D. J. New ingredients for brewing CD4(+)T (cells): TCF-1 and LEF-1. Nature Immunology. 2014. 15, 593-594. [PubMed]
3.
Mookerjee-Basu, J. , Vantourout, P., Martinez, L. O., Perret, B., Collet, X., Perigaud, C., Peyrottes, S. and Champagne, E. F1-adenosine triphosphatase displays properties characteristic of an antigen presentation molecule for Vgamma9Vdelta2 T cells. Journal of Immunology. 2010. 184, 6920-6928. [PubMed]
4.
Vantourout, P., Mookerjee-Basu, J. , Rolland, C., Pont, F., Martin, H., Davrinche, C., Martinez, L. O., Perret, B., Collet, X., Perigaud, C., Peyrottes, S. and Champagne, E. Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen. Journal of Immunology. 2009. 183, 3848-3857. [PubMed]
5.
Chatterjee, S., Mookerjee, A., Basu, J. M. , Chakraborty, P., Ganguly, A., Adhikary, A., Mukhopadhyay, D., Ganguli, S., Banerjee, R., Ashraf, M., Biswas, J., Das, P. K., Sa, G., Chatterjee, M., Das, T. and Choudhuri, S. K. A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells. PloS One. 2009. 4, e7048. [PubMed]
6.
Mookerjee, B. , Mookerjee, A., Banerjee, R., Saha, M., Singh, S., Naskar, K., Tripathy, G., Sinha, P. K., Pandey, K., Sundar, S., Bimal, S., Das, P. K., Choudhuri, S. K. and Roy, S. Inhibition of ABC transporters abolishes antimony resistance in Leishmania Infection. Antimicrobial Agents and Chemotherapy. 2008. 52, 1080-1093. [PubMed]
7.
Mookerjee, B. , Mookerjee, A., Sen, P., Bhaumik, S., Sen, P., Banerjee, S., Naskar, K., Choudhuri, S. K., Saha, B., Raha, S. and Roy, S. Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages. Antimicrobial Agents and Chemotherapy. 2006. 50, 1788-1797. [PubMed]
8.
Mookerjee, A., Mookerjee, B. , Dutta, P., Majumder, S., Bhattacharyya, S., Biswas, J., Pal, S., Mukherjee, P., Raha, S., Baral, R. N., Das, T., Efferth, T., Sa, G., Roy, S. and Choudhuri, S. K. Overcoming drug-resistant cancer by a newly developed copper chelate through host-protective cytokine-mediated apoptosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 2006. 12, 4339-4349. [PubMed]
Education
::
M.Sc. in Physiology, ,
University of Calcutta, Calcutta, India, 1997-1999
::
M.Tech. in Biotechnology,
Jadavpur University, Kolkata, India, 1999-2001
::
Ph.D. in Immunology and Infectous diseases,
Jadavpur University, Kolkata, India, 2001-2006