| |
Project Title |
Investigator/s |
Budget (Rs. In Lakhs) |
Date
of Sanction |
Duration
- years |
| 1. |
Cytokine
gene polymorphism in HPV associated cervical
cancer. |
Dr.
R. C. Sobti
Punjab University, Chandigarh. |
33.69 |
20.01.2005 |
5 |
| 2. |
HSP
90 in the regulation of Apoptosis in tumor
cells: Physiologically relevant examples of
antitumor therapics. |
Dr.
A. S. Sreedhar
CCMB, Hyderabad. |
18.15 |
27.01.2005 |
3 |
| 3. |
Human
papilloma viruses and prognosis of cervical
neoplasia. |
Dr.
Priya Abraham
CMC, Vellore. |
19.85 |
09.02.2005 |
3 |
| 4. |
Evaluation
of the oncogenic potential of signal transduction
domains of the Hepatitis-B virus X protein
in a transgenic environment. |
Dr.
Vijay Kumar
ICGEB, New Delhi. |
48.972 |
28.02.2005 |
3 |
| 5. |
Correlation
between the expression of sex steroid receptor
genes and tumor suppressor/inducer genes in
human thyroid cancer tissues. |
Dr.
M. Michael Aruldhas
University of Madras,
Chennai. |
45.97 |
09.03.2005 |
3 |
| 6. |
Characterization
of Testis specific Sperm associated antigen
9 (SPAG9) gene expression and humoral immune
response in various human cancers. |
Dr.
Anil Suri
NII, New Delhi. |
53.88 |
18.03.2005 |
3 |
| 7. |
Computer-Aided
Design of Novel NSAIDS as Selective Cyclooxygenase-2
(COX-2) Inhibitors as anticancer agents: Pilot
study for synthesis and preliminary activity
for its anti-tumor potential. |
Dr.
Madhu Chopra
BRA-CBR, Delhi. |
30.46 |
23.03.2005 |
3 |
| 8. |
Design,
Biotechnological production & in vivo evaluation
of comptohecin analogues for improved antitumor
activity. |
Dr.
Shubhangi Khedkar
SIES-IIEM, Mumbai. |
28.01 |
25.03.2005 |
3 |
| 9. |
Designing
of Methylation target arrays for Breast Cancer. |
Dr.
Ranju Ralhan
AIIMS, New Delhi. |
22.16 |
25.03.2005 |
1 |
| 10. |
Gene
therapy for head/neck cancer using combination
therapy: Immuno-Cytokine therapy plus pro-drug
activation therapy |
Dr.
Rita Mulherkar
ACTREC, Navi Mumbai. |
27.99 |
25.03.2005 |
2 |
| 11. |
Development
of HPV candidate vaccine/s: preparation of
clinical trial site/cohort for vaccine testing |
Dr.
Neerja Bhatla
AIIMS, N. Delhi. |
84.98 |
25.03.2005 |
3 |
| 12. |
Immune
responses to an Onco-fetal Antigen, hCG: A
Potential Anti-Cancer Immunotherapy. |
Dr.
Om Singh
NII, New Delhi |
29.89 |
31.03.2005 |
3 |
| 13. |
TLR
expression profile in Langerhans and Dendritic
Cells in invasive cervical cancer, cervical
intraepithelial neoplasia and chronic cervicitis. |
Dr.
R. S. Jayshree
KMIO, Bangalore. |
28.53 |
29.08.2005 |
3 |
| 14. |
Assessment
of the immune responses to HPV vaccine. A)
T and B cell responses in mice immunized with
HPV vaccine. B) In vitro lymphocyte responses
to HPV vaccine in healthy women exhibiting
presence of high titers of anti HPV antibodies. |
Dr.
Shubhada V. Chiplunkar
ACTREC, Navi Mumbai. |
65.37 |
31.10.2005 |
3 |
| 15. |
Suppression
of oral cancer-specific p53 mutants by SiRNA. |
Dr.
Uttam Pati
JNU, New Delhi. |
38.31 |
01.12.2005 |
3 |
| 16. |
Delineation
of Prognostic Biomarkers of progression of
cervical cancer. |
Dr.
Rita Mulherkar
ACTREC, Navi Mumbai. |
43.44 |
02.12.2005 |
4 |
| 17. |
Targeting
human lung cancer: A preclinical and mechanistic
investigation towards understanding lung metastasis. |
Dr.
Rajkumar Banerjee
IICT, Hyderabad |
61.50 |
08.12.2005 |
3 |
| 18. |
Role
of nuclear and mitochondrial genes in the aetiology
of uterine leiomyomata (fibroids) |
Dr.
Q. Hasan
VHRC, Hyderabad. |
17.10 |
09.12.2005 |
3 |
| 19. |
Identification
of Susceptibility Alleles for the Development
of Head and Neck Cancer in Indian Population. |
Dr.
Susanta Roychoudhury
IICB, Kolkata. |
77.61 |
29.11.2005 |
3 |
| 20. |
Role
of osteopontin, a chemokine like protein in
regulation of vascular endothelial growth factor
dependent tumor growth and angiogenesis in
breast cancer. |
Dr.
Gopal C. Kundu
NCCS, Pune. |
32.50 |
28.12.2005 |
3 |
| 21. |
Altered
Expression of tumor suppressor SMAR1 in breast
cancer causes deregulation of cyclin D1. |
Dr.
Samit Chattopadhyay
NCCS, Pune. |
67.89 |
04.01.2006 |
3 |
| 22. |
Small
Interfering RNA-Mediated inhibition of sperm
associated antigen 9 (SPAG9) expression in
the human cancer cell lines in in vitro and in
vivo. |
Dr.
Anil Suri
NII, New Delhi. |
17.13 |
08.03.2006 |
1.5 |
| 23. |
Role
of gap junctions in the bystander effect in
breast cancer cells. |
Dr.
P. Gajalakshmi
AU-KBC Research Centre, Chennai. |
13.27 |
28.03.2006 |
1.5 |
| 24. |
Identification
of novel esophageal squamous cell carcinoma
(ESCC) genes by using a combination of array
based CGH and gene expression microarrays. |
Dr.
Murali Dharan Bashyam
CDFD, Hyderabad. |
73.26 |
28.03.2006 |
3 |
| 25. |
Chemotherapeutic
role of pronyl-lysine against 1,2-dimethylhydrazine
induced colon cancer in male albino Wistar
rats. |
Dr.
N. Nalini
Annamalai University (T.N) |
26.66 |
28.03.2006 |
3 |
| 26. |
Studies
on genetic susceptibility factors in oral cancer
and precancer lesions with reference to metabolic
and DNA repair genes. |
Dr.
Manoj B Mahimkar
ACTREC, Navi Mumbai. |
15.81 |
28.03.2006 |
2 |
| 27. |
Design,
synthesis and biological evaluation of new
hybrids based on Pyrrolo[2,1-c] [1,4] benzodiazepines. |
Dr.
Ahmed Kamal
IICT, Hyderabad. |
50.56 |
28.03.2006 |
3 |
| 28. |
Role
of poly N-acetyl lactosamine substituted β1,6
branched N-oligosaccharides in facilitating
organ specific metastasis of melanoma cells
to the lungs. |
Dr.
Rajiv D Kalraiya
ACTREC, Navi Mumbai. |
31.92 |
28.03.2006 |
3 |
| 29. |
Study
of the signaling cascades involved in the proliferation
and differentiation of cancer stem cells in
Glioblastoma. |
Dr.
Ellora Sen
NBRC, Gurgaon. |
41.57 |
28.03.2006 |
3 |
| 30. |
Establishment
of molecular cytogenetics in combination with
protein markers for accurate diagnosis and
prognostic prediction of bone and soft tissue
sarcomas. |
Dr.
Pratibha S. Amare (Kadam)
TMC, Mumbai. |
17.70 |
11.05.2006 |
3 |
| 31. |
Regulatory
T cells: a potential marker of progression
of cervical precancer? |
Dr.
R. S. Jayshree
KMIO, Bangalore. |
41.96 |
10.07.2006 |
3.8 |
| 32. |
A
DNA repair gene-potential marker for Ovarian
cancer. |
Dr.
Nandan Bhattacharyya
HIT, West Bengal. |
24.56 |
23.10.2006 |
4.6 |
| 33. |
Molecular
monitoring of secondary mutations potentially
involved in disease transformation of CML to
CML-Blast Crisis. |
Dr.
Soumen Chakraborty
ILSc, Bhubaneswar. |
31.12 |
14.11.2006 |
3.5 |
| 34. |
Functional
characterization of LXR-α transcriptome
in psoriasis. |
Dr.
Davinder Prasad
PGIMER, Chandigarh. |
40.85 |
01.05.2007 |
3 |
| 35. |
Endothelial
progenitor cells as biomarker of disease activity
in multiple myeloma. |
Dr.
Lalit Kumar
AIIMS, New Delhi. |
18.81 |
21.05.2007 |
3 |
| 36. |
To
study the molecular biology of Multiple myeloma. |
Dr.
Lalit Kumar
IRCH-AIIMS, New Delhi. |
35.09 |
21.05.2007 |
3 |
| 37. |
Combination
of P53, EGFR status and tumor grading in determining
the outcome of early stage epithelial ovarian
cancers. |
Dr.
Lalit Kumar
IRCH-AIIMS, New Delhi. |
1.44 |
21.05.2007 |
1 |
| 38. |
Design
of novel anticancer drugs and analysis of their
therapeutic potential by in vitro and in vivo
studies. |
Dr.
Sartaj Tabassum
AMU, Aligarh. |
55.47 |
06.06.2007 |
3 |
| 39. |
Screening
for Human Papilloma Virus infection in the
population from Eastern UP. |
Dr.
J. K. Roy
BHU, Varanasi. |
18.28 |
07.06.2007 |
4 |
| 40. |
Molecular
mechanism of Intestinal Injury due to radiation
and chemotherapy and its protection by antioxidants,
in animal model. |
Dr.
S. Mahmood
PGIMER, Chandigarh. |
29.45 |
17.08.2007 |
2 |
| 41. |
Prospective
identification and clinical significance of
tumor progenitor cells in breast cancer. |
Dr.
Jem Prabhakar
RCC, Thiruvananthapuram. |
45.01 |
27.08.2007 |
3 |
| 42. |
Identification
and Functional characterization of the novel
variants of the tumor antigen SG2NA. |
Dr.
Shyamal K Goswami
JNU, New Delhi. |
38.15 |
14.09.2007 |
3 |
| 43. |
Evaluation
of putative mechanisms of anticataractogenic
effect of Acety1-L-Carnitine. |
Dr.
P. Geraldine
Bharathidasan University, Tamilnadu. |
49.61 |
21.09.2007 |
4 |
| 44. |
Immunotherapy
of drugs refractory leukemias and lymphomas
expressing hCG or subunits by a highly specific
recombinant chimeric antibody against β-hCG
linked to curcumin or other drugs. |
Dr.
G. P. Talwar
TRF, New Delhi. |
36.34 |
21.09.2007 |
2 |
| 45. |
An
in vitro silencing of endogenous oxidized-LDL-receptor
(LOX-1) gene by siRNA: Study of NF-kB activated
expression of proinflammatory cytokines and
related atherogenic proteins - its evaluation
against anti-inflammatory cytokine mediated
responses. |
Dr.
N. C. Chandra
AIIMS, New Delhi |
33.75 |
25.09.2007 |
4 |
| 46. |
Keratins
mediated regulation of apoptosis in stratified
epithelia and its role in acquisition of transformed
phenotype. |
Dr.
M. M. Vaidya
ACTREC, Navi Mumbai. |
31.59 |
25.09.2007 |
3 |
| 47. |
Development
and characterization of Autologous NKT Cell
based Dendritic Cell Vaccine for Active Specific
Immunotherapy of Oral Squamous Cell Carcinoma. |
Dr.
Satya N. Das
AIIMS, New Delhi. |
20.06 |
25.09.2007 |
3 |
| 48. |
Study
on the significance of Micro-RNA expression
pattern in oral carcinoma. |
Dr.
S. Kannan
RCC, Thiruvananthapuram. |
15.62 |
11.12.2007 |
2 |
| 49. |
Molecular
ecology, molecular genetics and natural history
of anterior tongue cancer in young adults without
(or insignificant) tobacco exposure: can a
distinct clinical entity be defined? |
Dr.
Paul Sebastian
RCC, Thrivananthapuram. |
34.34 |
13.11.2007 |
3 |
| 50. |
Molecular
Pathology of Cervical Carcinogenesis. |
Dr.
Gopeshwar Narayan
BHU, Varanasi. |
43.35 |
13.11.2007 |
4 |
| 51. |
Study
on gene expression and Hypermethylation profiles
in early onset breast cancer. |
Dr.
Sunita Saxena
Safdarjung Hospital, New Delhi. |
32.46 |
22.11.2007 |
3 |
| 52. |
Role
of Transcription Factor STAT3 in Human Papillomavirus
16 (HPV16) - Induced Cervical Carcinogenesis. |
Dr.
Alok C Bharti
ICPO, Noida |
43.01 |
27.11.2007 |
3 |
| 53. |
Cancer
testis antigens their importance in immunotherapy
and in early detection of cancer: Associated
Cancer Center for Immunotherapy. |
Dr.
Anil Suri
NII, New Delhi. |
62.47 |
21.01.2008 |
3 |
| 54. |
Development
of Adenovirus Herpes simplex Thymidine Kinase/
Ganciclovir strategy for Head and Neck squamous
cell carcinoma: Preclinical studies and large-scale
preparation of clinical grade vector. |
Dr.
Rita Mulherkar
ACTREC, Navi Mumbai. |
42.52 |
13.03.2008 |
2 |
| 55. |
Evaluation
of Prognostic Value of FDG-PET after two cycles
of Chemotherapy in Pediatric and Adolescent
High Grade Lymphomas. |
Dr.
Sameer Bakhshi
AIIMS, New Delhi. |
21.10 |
13.03.2008 |
3 |
| 56. |
Host-virus
interactions at the genetic and epigenetic
levels in HPV related cervical cancer in Indian
women. |
Dr.
Sharmila Sengupta
ISI, Kolkata. |
31.51 |
19.03.2008 |
3 |
| 57. |
DNMT3L:
epigenetic correlation with cancer. |
Dr.
Sanjeev Khosla
CDFD, Hyderabad. |
45.27 |
24.03.2008 |
3 |
| 58. |
Synthesis
and in-vitro mechanistic studies of
new metal-based anti-cancer agents. |
Dr.
Farukh Arjmand
AMU, Aligarh. |
29.05 |
21.06.2008 |
1.5 |
| 59. |
To
study the immune response of T cell dominant
synthetic peptides derived from HPV 16, using
different adjuvants in a mouse model of cervical
cancer. |
Dr.
Neeta Singh
AIIMS, New Delhi. |
27.00 |
10.09.2008 |
3 |
| 60. |
A
study of Mutational and Histopathological risk
factors for Gallbladder Cancer in patients
with Gallstones. |
Dr.
Pramod Kumar Garg
AIIMS, New Delhi. |
33.26 |
10.09.2008 |
3 |
| 61. |
Role
of E-Cadherin /β-Catenin Complex in the
progression of Gall Bladder Cancer. |
Prof.
V. K. Kapoor
SGPGIMS, Lucknow. |
58.32 |
16.09.2008 |
3 |
| 62. |
Determining
the role of BLM helicase in DNA damage signal
recognition and transduction due to double
strand breaks in human. |
Dr.
Sagar Sengupta
NII, New Delhi. |
43.64 |
18.09.2008 |
3 |
| 63. |
Evaluation
of circulating tumor DNA in serum of breast
cancer patients. |
Dr.
Vinod Raina
AIIMS, New Delhi. |
20.96 |
15.10.2008 |
3 |
| 64. |
Tumor
primordial cells in colorectal cancer: implications
for surgical margins and minimal residual disease. |
Dr.
S Asha Nair
RGCBT, Thiruvananthapuram. |
35.14 |
15.10.2008 |
3 |
| 65. |
Role
of STAT3 as downstream mediator of steroid
and epidermal growth factor pathways in breast
cancer. |
Dr.
Lakshmi .S
RCC, Thiruvananthapuram |
20.45 |
15.10.2008 |
3 |
| 66. |
Analysis
of Immunological parameters in breast tumors
in the context of age at diagnosis. |
Dr.
Narendra N. Joshi
ACTREC, Navi Mumbai. |
33.02 |
04.11.2008 |
3 |
| 67. |
Induction
of anti-tumor immunity by VEGF (vascular endothelial
growth factor) neutralization and CD40 activation. |
Dr.
Bhaskar Saha
NCCS, Pune. |
15.52 |
31.10.2008 |
1 |
| 68. |
A
study to evaluate the role of curcumin in oral
premalignant lesions and gingivo-buccal cancers |
Dr.
Anil D' Cruz
TMH, Mumbai |
72.42 |
30-12-2005 |
Closed
by DSMB |
| 69. |
Phase
II/III randomized placebo controlled clinical
trial of curcumin in respectable stage III
and IV squamous head and neck cancers (oral
cancers) |
Dr.
Alok Thakar
AIIMS, New Delhi |
87.61 |
05-12-2005 |
5+ |
| 70. |
Phase
II trial of curcumin in advanced Head and Neck
cancer treatment |
Dr.
Sunil K. Saini
HIMS, Dehradun |
20.04 |
06-01-2006 |
Completed |